The emergence of drug resistant strains has called the need for newer and novel antibiotics. More so, plants have shown promise as a source of diverse antibiotics. This research therefore reports the in vitro antibacterial activity of Plumeria rubra stem bark against Pseudomonas aeruginosa, Proteus mirabilis, Staphylococcus aureus, Aspergillus flavus, and Candida albicans. The stem bark of Plumeria rubra L. (Apocynaceae) from Plateau State extracted successively with dichloromethane (DCM), ethyl acetate (EA), and methanol (MET) gave yields of 8.34%, 9.57% and 17.65% respectively. The phytochemical screening carried out on the crude extracts showed the presence of balsams, terpenoids, steroids, saponins, flavonoids, cardiac glycosides and resins. The three crude extracts demonstrated activity against the test microorganisms with zones of inhibition ranging from 10 to 28mm, minimum inhibitory concentration (MIC) and minimum bacteriocidal concentration (MBC) ranging from 25-100mg/ml. The potency of these extracts is in the order methanol (MET), ethyl acetate (EA) and dichloromethane (DCM). This confirms the traditional use of this plant for the treatment of bacterial infection; however, the researchers did not examine the cytotoxicity of this plant extract
PAPER TITLE :IN VITRO ANTIMICROBIAL ACTIVITY OF STEM BARK EXTRACTS OF FRANGIPANI (PLUMERIA RUBRA) OBTAINED FROM P
JOURNAL Of SUSTAINABLE TECHNOLOGY | VOLUME 3 NUMBER 2 2012
Paper Details
- Author(s) : KAGORO, M.L. IBOK, N.U.2, and NARON, D.R
- Abstract:
