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Climate change is posing threat to existence of life. Many developing nations including Nigeria lack the necessary coping capability for the impact of climate change. It has therefore become necessary to integrate climate change concerns into spatial planning. This research aimed at assessing the human settlement adaptation strategies arising from climate change impacts in Asaba, Nigeria. The town was delineated into four clusters - Umuagu, Umuezeh, Ogbeumuata and Umuonaji. A sample size of 900 amounting to 4.2% of the total number of households was chosen. Using systematic random sampling procedure, respondents were selected in proportionate to the established household population in the various clusters. Data collected include level of awareness about climate change, household vulnerability to climate change impact and adaptation measures adopted by households. These data were analyzed and results presented with descriptive statistics including Tables, Charts and Figures. Identified adaptation strategies in the community include land filling, sinking of boreholes, adoption of aquaculture, increased in Damp Proof Course (DPC) level and tree planting to reduce the effect of urban heat island. The paper concluded that most of the adaptation strategies that were put in place are effective as they have relatively reduced the impacts of climate change in the study area. The research however canvassed for the establishment of climate change information systems that will facilitate robust awareness and promote early warning systems.  Other recommendations include provision of intensive training on       sustainable adaptive climate change strategies, identification of vulnerability hot spots and adoption of community penetrative public enlightenment on climate change phenomenon.